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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II

RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...

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Detalles Bibliográficos
Autores principales: Robinson, Christine, Lowe, Matthew, Schwartz, Amanda, Kikyo, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855949/
https://www.ncbi.nlm.nih.gov/pubmed/27158559
http://dx.doi.org/10.4172/2157-7633.1000330