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Mechanisms and Developmental Roles of Promoter-proximal Pausing of RNA Polymerase II
RNA polymerase II (Pol II) temporarily stops transcription after synthesizing 30–50 bases, and resumes elongation only after stimulations by various signaling molecules and developmental cues. This phenomenon, called promoter-proximal pausing, is observed in 10–50% of the entire genes from Drosophil...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855949/ https://www.ncbi.nlm.nih.gov/pubmed/27158559 http://dx.doi.org/10.4172/2157-7633.1000330 |