Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2/hemoxygenase-1 pathway by altering the balance of M1/M2 macrophages

BACKGROUND: Guillain–Barré syndrome (GBS) is an acute, post-infectious, immune-mediated, demyelinating disease of peripheral nerves and nerve roots. Dimethyl fumarate (DMF), a fumaric acid ester, exhibits various biological activities, including multiple immunomodulatory and neuroprotective effects....

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Detalles Bibliográficos
Autores principales: Han, Ranran, Xiao, Jinting, Zhai, Hui, Hao, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855950/
https://www.ncbi.nlm.nih.gov/pubmed/27142843
http://dx.doi.org/10.1186/s12974-016-0559-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855950/
https://www.ncbi.nlm.nih.gov/pubmed/27142843
http://dx.doi.org/10.1186/s12974-016-0559-x

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