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Strategies to generate high-titer, high-potency recombinant AAV3 serotype vectors

Although recombinant adeno-associated virus serotype 3 (AAV3) vectors were largely ignored previously, owing to their poor transduction efficiency in most cells and tissues examined, our initial observation of the selective tropism of AAV3 serotype vectors for human liver cancer cell lines and prima...

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Detalles Bibliográficos
Autores principales: Ling, Chen, Yin, Zifei, Li, Jun, Zhang, Daniel, Aslanidi, George, Srivastava, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856060/
https://www.ncbi.nlm.nih.gov/pubmed/27200382
http://dx.doi.org/10.1038/mtm.2016.29