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Mapping Challenging Mutations by Whole-Genome Sequencing

Whole-genome sequencing provides a rapid and powerful method for identifying mutations on a global scale, and has spurred a renewed enthusiasm for classical genetic screens in model organisms. The most commonly characterized category of mutation consists of monogenic, recessive traits, due to their...

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Detalles Bibliográficos
Autores principales: Smith, Harold E., Fabritius, Amy S., Jaramillo-Lambert, Aimee, Golden, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856081/
https://www.ncbi.nlm.nih.gov/pubmed/26945029
http://dx.doi.org/10.1534/g3.116.028316