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Mapping Challenging Mutations by Whole-Genome Sequencing
Whole-genome sequencing provides a rapid and powerful method for identifying mutations on a global scale, and has spurred a renewed enthusiasm for classical genetic screens in model organisms. The most commonly characterized category of mutation consists of monogenic, recessive traits, due to their...
Autores principales: | Smith, Harold E., Fabritius, Amy S., Jaramillo-Lambert, Aimee, Golden, Andy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856081/ https://www.ncbi.nlm.nih.gov/pubmed/26945029 http://dx.doi.org/10.1534/g3.116.028316 |
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