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The HIST1 Locus Escapes Reprogramming in Cloned Bovine Embryos

Epigenetic reprogramming is necessary in somatic cell nuclear transfer (SCNT) embryos in order to erase the differentiation-associated epigenetic marks of donor cells. However, such epigenetic memories often persist throughout the course of clonal development, thus decreasing cloning efficiency. Her...

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Detalles Bibliográficos
Autores principales: Min, Byungkuk, Cho, Sunwha, Park, Jung Sun, Jeon, Kyuheum, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856087/
https://www.ncbi.nlm.nih.gov/pubmed/26976441
http://dx.doi.org/10.1534/g3.115.026666