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Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

About two-thirds of the vital genes in the Drosophila genome are involved in eye development, making the fly eye an excellent genetic system to study cellular function and development, neurodevelopment/degeneration, and complex diseases such as cancer and diabetes. We developed a novel computational...

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Detalles Bibliográficos
Autores principales: Iyer, Janani, Wang, Qingyu, Le, Thanh, Pizzo, Lucilla, Grönke, Sebastian, Ambegaokar, Surendra S., Imai, Yuzuru, Srivastava, Ashutosh, Troisí, Beatriz Llamusí, Mardon, Graeme, Artero, Ruben, Jackson, George R., Isaacs, Adrian M., Partridge, Linda, Lu, Bingwei, Kumar, Justin P., Girirajan, Santhosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856093/
https://www.ncbi.nlm.nih.gov/pubmed/26994292
http://dx.doi.org/10.1534/g3.116.027060