Diurnal variation in cholesterol 7α-hydroxylase activity is determined by the -203A>C polymorphism of the CYP7A1 gene

AIM: To determine whether the promoter polymorphism -203A>C of cholesterol-7α-hydroxylase encoding gene (CYP7A1) affects diurnal variation in CYP7A1 enzyme activity. METHODS: The study included 16 healthy male volunteers – 8 homozygous for -203A and 8 homozygous for the -203C allele of CYP7A1. Th...

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Detalles Bibliográficos
Autores principales: Vlachová, Miluše, Blahová, Tereza, Lánská, Věra, Leníček, Martin, Piťha, Jan, Vítek, Libor, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2016
Materias:
RECOOP for Common Mechanisms of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856193/
https://www.ncbi.nlm.nih.gov/pubmed/27106353
http://dx.doi.org/10.3325/cmj.2016.57.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856193/
https://www.ncbi.nlm.nih.gov/pubmed/27106353
http://dx.doi.org/10.3325/cmj.2016.57.111

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