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Putative anticancer potential of novel 4-thiazolidinone derivatives: cytotoxicity toward rat C6 glioma in vitro and correlation of general toxicity with the balance of free radical oxidation in rats

AIM: To evaluate the cytotoxic action of 4-thiazolidinone derivatives (ID 3288, ID 3882, and ID 3833) toward rat glioma C6 cells and to compare the effects of these compounds and doxorubicin on the balance of free radical oxidation (FRO) and antioxidant activity (AOA) in the serum of rats. METHODS:...

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Detalles Bibliográficos
Autores principales: Коbylinska, Lesya I., Boiko, Nataliya M., Panchuk, Rostyslav R., Grytsyna, Iryna I., Klyuchivska, Olga Yu., Biletska, Liliya P., Lesyk, Roman B., Zіmenkovsky, Borys S., Stoika, Rostyslav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856196/
https://www.ncbi.nlm.nih.gov/pubmed/27106357
http://dx.doi.org/10.3325/cmj.2016.57.151