Interleukin 6/Wnt interactions in rheumatoid arthritis: interleukin 6 inhibits Wnt signaling in synovial fibroblasts and osteoblasts

AIM: To evaluate the impact of previously unrecognized negative interaction between the Wnt and interleukin (IL) 6 signaling pathways in skeletal tissues as a possible major mechanism leading to age- and inflammation-related destruction of bone and joints. METHODS: Luciferase reporter assays were pe...

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Detalles Bibliográficos
Autores principales: Malysheva, Khrystyna, de Rooij, Karien, Löwik, Clemens W. G. M., Baeten, Dominique L., Rose-John, Stefan, Stoika, Rostyslav, Korchynskyi, Olexandr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2016
Materias:
RECOOP for Common Mechanisms of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856197/
https://www.ncbi.nlm.nih.gov/pubmed/27106351
http://dx.doi.org/10.3325/cmj.2016.57.89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856197/
https://www.ncbi.nlm.nih.gov/pubmed/27106351
http://dx.doi.org/10.3325/cmj.2016.57.89

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