Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs

GRP78, a member of the ER stress protein family, can relocate to the surface of cancer cells, playing key roles in promoting cell proliferation and metastasis. GRP78 consists of two major functional domains: the ATPase and protein/peptide-binding domains. The protein/peptide-binding domain of cell-s...

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Detalles Bibliográficos
Autores principales: Hughes, Scott J., Antoshchenko, Tetyana, Chen, Yun, Lu, Hua, Pizarro, Juan C., Park, Hee-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856263/
https://www.ncbi.nlm.nih.gov/pubmed/27144892
http://dx.doi.org/10.1371/journal.pone.0154862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856263/
https://www.ncbi.nlm.nih.gov/pubmed/27144892
http://dx.doi.org/10.1371/journal.pone.0154862

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