Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

A central challenge in the analysis of genetic variation is to provide realistic genome simulation across millions of samples. Present day coalescent simulations do not scale well, or use approximations that fail to capture important long-range linkage properties. Analysing the results of simulation...

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Detalles Bibliográficos
Autores principales: Kelleher, Jerome, Etheridge, Alison M, McVean, Gilean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856371/
https://www.ncbi.nlm.nih.gov/pubmed/27145223
http://dx.doi.org/10.1371/journal.pcbi.1004842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856371/
https://www.ncbi.nlm.nih.gov/pubmed/27145223
http://dx.doi.org/10.1371/journal.pcbi.1004842

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