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Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes
A central challenge in the analysis of genetic variation is to provide realistic genome simulation across millions of samples. Present day coalescent simulations do not scale well, or use approximations that fail to capture important long-range linkage properties. Analysing the results of simulation...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856371/ https://www.ncbi.nlm.nih.gov/pubmed/27145223 http://dx.doi.org/10.1371/journal.pcbi.1004842 |