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Shortened Lifespan and Lethal Hemorrhage in a Hemophilia A Mouse Model
BACKGROUND: Hemophilia A animal models have helped advance our understanding of factor VIII deficiency. Previously, factor VIII deficient mouse models were reported to have a normal life span without spontaneous bleeds. However, the bleeding frequency and survival in these animals has not been thoro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856382/ https://www.ncbi.nlm.nih.gov/pubmed/27144769 http://dx.doi.org/10.1371/journal.pone.0154857 |