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A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome

BACKGROUND: Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L. braziliensis pathogenesis or response to chemotherapy in vivo due to the natural resistance...

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Detalles Bibliográficos
Autores principales: Coelho, Adriano C., Oliveira, Jordana C., Espada, Caroline R., Reimão, Juliana Q., Trinconi, Cristiana T., Uliana, Silvia R. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856402/
https://www.ncbi.nlm.nih.gov/pubmed/27144739
http://dx.doi.org/10.1371/journal.pntd.0004660