Cargando…
A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome
BACKGROUND: Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L. braziliensis pathogenesis or response to chemotherapy in vivo due to the natural resistance...
Autores principales: | Coelho, Adriano C., Oliveira, Jordana C., Espada, Caroline R., Reimão, Juliana Q., Trinconi, Cristiana T., Uliana, Silvia R. B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856402/ https://www.ncbi.nlm.nih.gov/pubmed/27144739 http://dx.doi.org/10.1371/journal.pntd.0004660 |
Ejemplares similares
-
Generation of Luciferase-Expressing Leishmania infantum chagasi and Assessment of Miltefosine Efficacy in Infected Hamsters through Bioimaging
por: Reimão, Juliana Q., et al.
Publicado: (2015) -
Ros3 (Lem3p/CDC50) Gene Dosage Is Implicated in Miltefosine
Susceptibility in Leishmania (Viannia) braziliensis Clinical Isolates and in Leishmania (Leishmania) major
por: Espada, Caroline R., et al.
Publicado: (2021) -
In Vitro and In Vivo Miltefosine Susceptibility of a Leishmania amazonensis Isolate from a Patient with Diffuse Cutaneous Leishmaniasis
por: Coelho, Adriano C., et al.
Publicado: (2014) -
In Vitro and In Vivo Miltefosine Susceptibility of a Leishmania amazonensis Isolate from a Patient with Diffuse Cutaneous Leishmaniasis: Follow-Up
por: Coelho, Adriano C., et al.
Publicado: (2016) -
Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake
por: Espada, Caroline R., et al.
Publicado: (2019)