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ATP half‐sites in RadA and RAD51 recombinases bind nucleotides

Homologous recombination is essential for repair of DNA double‐strand breaks. Central to this process is a family of recombinases, including archeal RadA and human RAD51, which form nucleoprotein filaments on damaged single‐stranded DNA ends and facilitate their ATP‐dependent repair. ATP binding and...

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Detalles Bibliográficos
Autores principales: Marsh, May E., Scott, Duncan E., Ehebauer, Matthias T., Abell, Chris, Blundell, Tom L., Hyvönen, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856416/
https://www.ncbi.nlm.nih.gov/pubmed/27419043
http://dx.doi.org/10.1002/2211-5463.12052