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Activities of wild‐type and variant tissue‐type plasminogen activators retained on vascular endothelial cells

We reported that tissue‐type plasminogen activator (tPA) secreted from vascular endothelial cells (VECs) is retained on the cell surface and effectively evokes both plasminogen activation and fibrin clot dissolution (fibrinolysis) on VECs. Here, to evaluate possibly different behaviors of variants o...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuko, Sano, Hideto, Tomczyk, Martyna, Brzoska, Tomasz, Urano, Tetsumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856425/
https://www.ncbi.nlm.nih.gov/pubmed/27419052
http://dx.doi.org/10.1002/2211-5463.12057