Assessment of FBA Based Gene Essentiality Analysis in Cancer with a Fast Context-Specific Network Reconstruction Method

MOTIVATION: Gene Essentiality Analysis based on Flux Balance Analysis (FBA-based GEA) is a promising tool for the identification of novel metabolic therapeutic targets in cancer. The reconstruction of cancer-specific metabolic networks, typically based on gene expression data, constitutes a sensible...

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Detalles Bibliográficos
Autores principales: Tobalina, Luis, Pey, Jon, Rezola, Alberto, Planes, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856428/
https://www.ncbi.nlm.nih.gov/pubmed/27145226
http://dx.doi.org/10.1371/journal.pone.0154583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856428/
https://www.ncbi.nlm.nih.gov/pubmed/27145226
http://dx.doi.org/10.1371/journal.pone.0154583

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