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PKC iota promotes ovarian tumor progression through deregulation of cyclin E

The high frequency of relapse of epithelial ovarian tumors treated with standard chemotherapy has highlighted the necessity to identify targeted therapies that can improve patient outcomes. The dynamic relationship between Cyclin E and PKCiota frequent overexpression in high-grade ovarian tumors pos...

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Detalles Bibliográficos
Autores principales: Nanos-Webb, Angela, Bui, Tuyen, Karakas, Cansu, Zhang, Dong, Carey, Jason P.W., Mills, Gordon B., Hunt, Kelly K., Keyomarsi, Khandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856585/
https://www.ncbi.nlm.nih.gov/pubmed/26279297
http://dx.doi.org/10.1038/onc.2015.301