Recent Advances in Development and Application of Physiologically-Based Pharmacokinetic (PBPK) Models: a Transition from Academic Curiosity to Regulatory Acceptance

There is a renewed surge of interest in applications of physiologically-based pharmacokinetic (PBPK) models by the pharmaceutical industry and regulatory agencies. Developing PBPK models within a systems pharmacology context allows separation of the parameters pertaining to the animal or human body...

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Detalles Bibliográficos
Autor principal: Jamei, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Pharmacometrics (H Kimko, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856711/
https://www.ncbi.nlm.nih.gov/pubmed/27226953
http://dx.doi.org/10.1007/s40495-016-0059-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856711/
https://www.ncbi.nlm.nih.gov/pubmed/27226953
http://dx.doi.org/10.1007/s40495-016-0059-9

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