A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies

Treatment of disseminated tuberculosis in children ≤ 6 years has not been optimized. The pyrazinamide-containing combination regimen used to treat disseminated tuberculosis in babies and toddlers was extrapolated from adult pulmonary tuberculosis. Due to hepatotoxicity worries, there are no dose–res...

Descripción completa

Detalles Bibliográficos
Autores principales: Srivastava, Shashikant, Pasipanodya, Jotam G., Ramachandran, Geetha, Deshpande, Devyani, Shuford, Stephen, Crosswell, Howland E., Cirrincione, Kayle N., Sherman, Carleton M., Swaminathan, Soumya, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856747/
https://www.ncbi.nlm.nih.gov/pubmed/27211555
http://dx.doi.org/10.1016/j.ebiom.2016.02.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856747/
https://www.ncbi.nlm.nih.gov/pubmed/27211555
http://dx.doi.org/10.1016/j.ebiom.2016.02.040

Ejemplares similares