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Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study

BACKGROUND: Type 2 diabetes (T2D) is a risk factor for dysregulation of glomerular filtration rate (GFR) and albuminuria. However, whether the association is causal remains unestablished. RESEARCH DESIGN AND METHODS: We performed a Mendelian Randomization (MR) analysis in 11,502 participants aged 40...

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Detalles Bibliográficos
Autores principales: Xu, Min, Bi, Yufang, Huang, Ya, Xie, Lan, Hao, Mingli, Zhao, Zhiyun, Xu, Yu, Lu, Jieli, Chen, Yuhong, Sun, Yimin, Qi, Lu, Wang, Weiqing, Ning, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856750/
https://www.ncbi.nlm.nih.gov/pubmed/27211558
http://dx.doi.org/10.1016/j.ebiom.2016.02.032