Trans-ethnic study design approaches for fine-mapping

Studies that traverse ancestrally diverse populations may increase power to detect novel loci and improve fine-mapping resolution of causal variants by leveraging linkage disequilibrium differences between ethnic groups. The inclusion of African ancestry samples may yield further improvements becaus...

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Detalles Bibliográficos
Autores principales: Asimit, Jennifer L, Hatzikotoulas, Konstantinos, McCarthy, Mark, Morris, Andrew P, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856879/
https://www.ncbi.nlm.nih.gov/pubmed/26839038
http://dx.doi.org/10.1038/ejhg.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856879/
https://www.ncbi.nlm.nih.gov/pubmed/26839038
http://dx.doi.org/10.1038/ejhg.2016.1

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