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The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases
High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856949/ https://www.ncbi.nlm.nih.gov/pubmed/27175328 http://dx.doi.org/10.1016/j.apsb.2016.02.004 |