The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases

High mobility group box 1 (HMGB1) is a nuclear protein that can bind to DNA and act as a co-factor for gene transcription. When released into extracellular fluid, it plays a proinflammatory role by acting as a damage-associated molecular pattern molecule (DAMP) (also known as an alarmin) to initiate...

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Detalles Bibliográficos
Autores principales: Chen, Qingjie, Guan, Xiaofeng, Zuo, Xiaocong, Wang, Jianglin, Yin, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856949/
https://www.ncbi.nlm.nih.gov/pubmed/27175328
http://dx.doi.org/10.1016/j.apsb.2016.02.004

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