Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability

Maintenance of proper chromatin states and genomic stability is vital for normal development and health across a range of organisms. Here, we report on the role of KLLN in maintenance of pericentric H3K9 trimethylation (H3K9me3) and genomic stability. Germline hypermethylation of KLLN, a gene uncove...

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Detalles Bibliográficos
Autores principales: Nizialek, Emily A., Sankunny, Madhav, Niazi, Farshad, Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856962/
https://www.ncbi.nlm.nih.gov/pubmed/26673699
http://dx.doi.org/10.1093/nar/gkv1481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856962/
https://www.ncbi.nlm.nih.gov/pubmed/26673699
http://dx.doi.org/10.1093/nar/gkv1481

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