G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV

Kaposi's sarcoma associated herpesvirus (KSHV) establishes life-long latent infection by persisting as an extra-chromosomal episome in the infected cells and by maintaining its genome in dividing cells. KSHV achieves this by tethering its epigenome to the host chromosome by latency associated n...

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Detalles Bibliográficos
Autores principales: Madireddy, Advaitha, Purushothaman, Pravinkumar, Loosbroock, Christopher P., Robertson, Erle S., Schildkraut, Carl L., Verma, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856979/
https://www.ncbi.nlm.nih.gov/pubmed/26837574
http://dx.doi.org/10.1093/nar/gkw038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856979/
https://www.ncbi.nlm.nih.gov/pubmed/26837574
http://dx.doi.org/10.1093/nar/gkw038

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