A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes

The folding topology of DNA G-quadruplexes (G4s) depends not only on their nucleotide sequences but also on environmental factors and/or ligand binding. Here, a G4 ligand, 3,6-bis(1-methyl-4-vinylpyridium iodide)-9-(1-(1-methyl-piperidinium iodide)-3,6,9-trioxaundecane) carbazole (BMVC-8C3O), can in...

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Detalles Bibliográficos
Autores principales: Wang, Zi-Fu, Li, Ming-Hao, Chen, Wei-Wen, Hsu, Shang-Te Danny, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856992/
https://www.ncbi.nlm.nih.gov/pubmed/26975658
http://dx.doi.org/10.1093/nar/gkw145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856992/
https://www.ncbi.nlm.nih.gov/pubmed/26975658
http://dx.doi.org/10.1093/nar/gkw145

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