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Noncanonical registers and base pairs in human 5′ splice-site selection

Accurate recognition of splice sites is essential for pre-messenger RNA splicing. Mammalian 5′ splice sites are mainly recognized by canonical base-pairing to the 5′ end of U1 small nuclear RNA, yet we described multiple noncanonical base-pairing registers by shifting base-pair positions or allowing...

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Detalles Bibliográficos
Autores principales: Tan, Jiazi, Ho, Jia Xin Jessie, Zhong, Zhensheng, Luo, Shufang, Chen, Gang, Roca, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856993/
https://www.ncbi.nlm.nih.gov/pubmed/26969736
http://dx.doi.org/10.1093/nar/gkw163