Pif1 removes a Rap1-dependent barrier to the strand displacement activity of DNA polymerase δ

Using an in vitro reconstituted system in this work we provide direct evidence that the yeast repressor/activator protein 1 (Rap1), tightly bound to its consensus site, forms a strong non-polar barrier for the strand displacement activity of DNA polymerase δ. We propose that relief of inhibition may...

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Detalles Bibliográficos
Autores principales: Koc, Katrina N., Singh, Saurabh P., Stodola, Joseph L., Burgers, Peter M., Galletto, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856994/
https://www.ncbi.nlm.nih.gov/pubmed/27001517
http://dx.doi.org/10.1093/nar/gkw181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856994/
https://www.ncbi.nlm.nih.gov/pubmed/27001517
http://dx.doi.org/10.1093/nar/gkw181

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