Molecularly resolved label-free sensing of single nucleobase mismatches by interfacial LNA probes

So far, there has been no report on molecularly resolved discrimination of single nucleobase mismatches using surface-confined single stranded locked nucleic acid (ssLNA) probes. Herein, it is exemplified using a label-independent force-sensing approach that an optimal coverage of 12-mer ssLNA senso...

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Detalles Bibliográficos
Autores principales: Mishra, Sourav, Lahiri, Hiya, Banerjee, Siddhartha, Mukhopadhyay, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856997/
https://www.ncbi.nlm.nih.gov/pubmed/27025649
http://dx.doi.org/10.1093/nar/gkw197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856997/
https://www.ncbi.nlm.nih.gov/pubmed/27025649
http://dx.doi.org/10.1093/nar/gkw197

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