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MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1

MiR-26 has emerged as a key tumour suppressor in various cancers. Accumulating evidence supports that miR-26 regulates inflammation and tumourigenicity largely through down-regulating IL-6 production, but the underlying mechanism remains obscure. Here, combining a transcriptome-wide approach with ma...

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Detalles Bibliográficos
Autores principales: Chen, Chyi-Ying A., Chang, Jeffrey T., Ho, Yi-Fang, Shyu, Ann-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856999/
https://www.ncbi.nlm.nih.gov/pubmed/27025651
http://dx.doi.org/10.1093/nar/gkw205