A potential adjuvant chemotherapeutics, 18β-glycyrrhetinic acid, inhibits renal tubular epithelial cells apoptosis via enhancing BMP-7 epigenetically through targeting HDAC2

Cisplatin, a highly effective and widely used chemotherapeutic agent, has a major limitation for its nephrotoxicity. We recently identified a novel strategy for attenuating its nephrotoxicity in chemotherapy by an effective adjuvant via epigenetic modification through targeting HDAC2. Molecular dock...

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Detalles Bibliográficos
Autores principales: Ma, Taotao, Huang, Cheng, Meng, Xiaoming, Li, Xiaofeng, Zhang, Yilong, Ji, Shuai, Li, Jun, Ye, Min, Liang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857087/
https://www.ncbi.nlm.nih.gov/pubmed/27145860
http://dx.doi.org/10.1038/srep25396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857087/
https://www.ncbi.nlm.nih.gov/pubmed/27145860
http://dx.doi.org/10.1038/srep25396

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