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Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2

Polycomb group (PcG) proteins are transcriptional repressors of numerous genes, many of which regulate cell cycle progression or developmental processes. We used zebrafish to study Enhancer of zeste homolog 2 (Ezh2), the PcG protein responsible for placing the transcriptional repressive H3K27me3 mar...

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Detalles Bibliográficos
Autores principales: San, Bilge, Chrispijn, Naomi D., Wittkopp, Nadine, van Heeringen, Simon J., Lagendijk, Anne K., Aben, Marco, Bakkers, Jeroen, Ketting, René F., Kamminga, Leonie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857124/
https://www.ncbi.nlm.nih.gov/pubmed/27145952
http://dx.doi.org/10.1038/srep24658