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Mechanistic and quantitative insight into cell surface targeted molecular imaging agent design

Molecular imaging agent design involves simultaneously optimizing multiple probe properties. While several desired characteristics are straightforward, including high affinity and low non-specific background signal, in practice there are quantitative trade-offs between these properties. These includ...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Bhatnagar, Sumit, Deschenes, Emily, Thurber, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857130/
https://www.ncbi.nlm.nih.gov/pubmed/27147293
http://dx.doi.org/10.1038/srep25424