Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest

Cell cycle regulation is critical for chondrocyte differentiation and hypertrophy. Recently we identified the Notch signaling pathway as an important regulator of chondrocyte proliferation and differentiation during mouse cartilage development. To investigate the underlying mechanisms, we assessed t...

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Detalles Bibliográficos
Autores principales: Shang, Xifu, Wang, Jinwu, Luo, Zhengliang, Wang, Yongjun, Morandi, Massimo M., Marymont, John V., Hilton, Matthew J., Dong, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857138/
https://www.ncbi.nlm.nih.gov/pubmed/27146698
http://dx.doi.org/10.1038/srep25594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857138/
https://www.ncbi.nlm.nih.gov/pubmed/27146698
http://dx.doi.org/10.1038/srep25594

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