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Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest
Cell cycle regulation is critical for chondrocyte differentiation and hypertrophy. Recently we identified the Notch signaling pathway as an important regulator of chondrocyte proliferation and differentiation during mouse cartilage development. To investigate the underlying mechanisms, we assessed t...
Autores principales: | Shang, Xifu, Wang, Jinwu, Luo, Zhengliang, Wang, Yongjun, Morandi, Massimo M., Marymont, John V., Hilton, Matthew J., Dong, Yufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857138/ https://www.ncbi.nlm.nih.gov/pubmed/27146698 http://dx.doi.org/10.1038/srep25594 |
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