RBFOX1 and RBFOX2 are dispensable in iPSCs and iPSC-derived neurons and do not contribute to neural-specific paternal UBE3A silencing

Angelman Syndrome (AS) is a rare neurodevelopmental disorder caused by loss of function of the maternally inherited copy of UBE3A, an imprinted gene expressed biallelically in most tissues, but expressed exclusively from the maternal allele in neurons. Active transcription of the neuron-specific lon...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Pin-Fang, Hsiao, Jack S., Sirois, Carissa L., Chamberlain, Stormy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857170/
https://www.ncbi.nlm.nih.gov/pubmed/27146458
http://dx.doi.org/10.1038/srep25368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857170/
https://www.ncbi.nlm.nih.gov/pubmed/27146458
http://dx.doi.org/10.1038/srep25368

Ejemplares similares