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Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain

BACKGROUND: Despite substantial progress, pathogenesis and therapy of chronic pain are still the focus of many investigations. The ATP-gated P2X7 receptor (P2X7R) has previously been shown to play a central role in animal models of nociceptive inflammatory and neuropathic pain. Recently, we found th...

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Detalles Bibliográficos
Autores principales: Luchting, Benjamin, Heyn, Jens, Woehrle, Tobias, Rachinger-Adam, Banafscheh, Kreth, Simone, Hinske, Ludwig C, Azad, Shahnaz C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857287/
https://www.ncbi.nlm.nih.gov/pubmed/27145808
http://dx.doi.org/10.1186/s12974-016-0565-z