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Spontaneous development of neoplasms in severe combined immunodeficient mice
Severe combined immunodeficient (SCID) mice lack functional T and B cells. This renders them useful for implantation of human cells. The absence of immune cells, however, makes severe combined immunodeficient mice highly susceptible to infections and spontaneous development of malignancies; 2 of 114...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857314/ https://www.ncbi.nlm.nih.gov/pubmed/27489678 http://dx.doi.org/10.1177/2050313X14568698 |