Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness

Individual cells within a tumour can exhibit distinct genetic and molecular features. The impact of such diversification on metastatic potential is unknown. Here we identify clonal human breast cancer subpopulations that display different levels of morphological and molecular diversity. Highly varia...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Alexander, Yoshida, Mitsukuni, Goodarzi, Hani, Tavazoie, Sohail F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857405/
https://www.ncbi.nlm.nih.gov/pubmed/27138336
http://dx.doi.org/10.1038/ncomms11246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857405/
https://www.ncbi.nlm.nih.gov/pubmed/27138336
http://dx.doi.org/10.1038/ncomms11246

Ejemplares similares