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Osteoblastic differentiation of bone marrow mesenchymal stromal cells in Bruck Syndrome

BACKGROUND: Osteogenesis Imperfecta (OI) (OMIM %259450) is a heterogeneous group of inherited disorders characterized by increased bone fragility, with clinical severity ranging from mild to lethal. The majority of OI cases are caused by mutations in COL1A1 or COL1A2. Bruck Syndrome (BS) is a furthe...

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Detalles Bibliográficos
Autores principales: Kaneto, Carla M., Lima, Patrícia S. P., Zanette, Dalila Lucíola, Oliveira, Thiago Yukio Kikuchi, de Assis Pereira, Francisco, Lorenzi, Julio Cesar Cetrulo, dos Santos, Jane Lima, Prata, Karen L., Neto, João M. Pina, de Paula, Francisco J. A., Silva, Wilson A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857408/
https://www.ncbi.nlm.nih.gov/pubmed/27146342
http://dx.doi.org/10.1186/s12881-016-0301-7