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Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

BACKGROUND: Angiogenesis inhibition is a promising approach for treating metastatic colorectal cancer (mCRC). Recent evidences support the seemingly counterintuitive ability of certain antiangiogenic drugs to promote normalization of residual tumor vessels with important clinical implications. Lenal...

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Bibliografiske detaljer
Autores principales: Leuci, V., Maione, F., Rotolo, R., Giraudo, E., Sassi, F., Migliardi, G., Todorovic, M., Gammaitoni, L., Mesiano, G., Giraudo, L., Luraghi, P., Leone, F., Bussolino, F., Grignani, G., Aglietta, M., Trusolino, L., Bertotti, A., Sangiolo, D.
Format: Online Artículo Texto
Sprog:English
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857418/
https://www.ncbi.nlm.nih.gov/pubmed/27149858
http://dx.doi.org/10.1186/s12967-016-0872-2