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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples
BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with different molecular characteristics associated with many variables such as the sites from which the tumors originate or the presence or absence of chromosomal instability. Identification of such variables, particularly mutational ho...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857423/ https://www.ncbi.nlm.nih.gov/pubmed/27146902 http://dx.doi.org/10.1186/s12967-016-0878-9 |