Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with different molecular characteristics associated with many variables such as the sites from which the tumors originate or the presence or absence of chromosomal instability. Identification of such variables, particularly mutational ho...

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Detalles Bibliográficos
Autores principales: Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Ahwal, Mahmoud Shaheen, Al-Maghrabi, Jaudah, Bajouh, Osama, Al-Khayyat, Shadi, Alam, Rania, Abusanad, Atlal, Turki, Rola, Elaimi, Aisha, Alhadrami, Hani A., Abuzenadah, Mohammed, Banni, Huda, Al-Qahtani, Mohammed H., Abuzenadah, Adel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857423/
https://www.ncbi.nlm.nih.gov/pubmed/27146902
http://dx.doi.org/10.1186/s12967-016-0878-9

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