DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing

BACKGROUND: The targeting of disease-related proteins is important for drug discovery, and yet target-based discovery has not been fruitful. Contextualizing overall biological processes is critical to formulating successful drug-disease hypotheses. Network pharmacology helps to overcome target-based...

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Detalles Bibliográficos
Autores principales: Issa, Naiem T., Kruger, Jordan, Wathieu, Henri, Raja, Rajarajan, Byers, Stephen W., Dakshanamurthy, Sivanesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857427/
https://www.ncbi.nlm.nih.gov/pubmed/27151405
http://dx.doi.org/10.1186/s12859-016-1065-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857427/
https://www.ncbi.nlm.nih.gov/pubmed/27151405
http://dx.doi.org/10.1186/s12859-016-1065-y

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