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DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing
BACKGROUND: The targeting of disease-related proteins is important for drug discovery, and yet target-based discovery has not been fruitful. Contextualizing overall biological processes is critical to formulating successful drug-disease hypotheses. Network pharmacology helps to overcome target-based...
Autores principales: | Issa, Naiem T., Kruger, Jordan, Wathieu, Henri, Raja, Rajarajan, Byers, Stephen W., Dakshanamurthy, Sivanesan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857427/ https://www.ncbi.nlm.nih.gov/pubmed/27151405 http://dx.doi.org/10.1186/s12859-016-1065-y |
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