Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus–Responsive CD4(+) and CD8(+) T Cells at the Human Intestinal Mucosa

Background. Oral vaccination with live-attenuated Salmonella Typhi strain Ty21a is modestly efficacious, but the mechanisms of protection are currently unknown. While humoral and cellular immune responses are well described in peripheral blood, the cellular response at the intestinal mucosa has neve...

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Detalles Bibliográficos
Autores principales: Pennington, Shaun H., Thompson, Ameeka L., Wright, Adam K. A., Ferreira, Daniela M., Jambo, Kondwani C., Wright, Angela D., Faragher, Brian, Gilmour, Jill W., Gordon, Stephen B., Gordon, Melita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857474/
https://www.ncbi.nlm.nih.gov/pubmed/26810369
http://dx.doi.org/10.1093/infdis/jiw030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857474/
https://www.ncbi.nlm.nih.gov/pubmed/26810369
http://dx.doi.org/10.1093/infdis/jiw030

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